College Football · 2026

Louisville Cardinals

Schedule, closing lines and results against the spread for the 2026 season.

2026 schedule

1. Sun, Sep 6Week 1@ Ole MissL 38-41Line+6.5WTotal54.5O
2. Fri, Sep 11Week 2vs VillanovaW 59-13Line−39.5WTotal56.5O
3. Sat, Sep 19Week 3vs SMUW 41-31Line−3WTotal57.5O
4. Sat, Sep 26Week 4vs Wake ForestL 27-30Line−11.5LTotal57.5U
5. Sat, Oct 3Week 5@ NC StateL 28-31Line−5.5LTotal56.5O
6. Fri, Oct 9Week 6vs Florida StateW 44-20Line−4WTotal60.5O
7. Sat, Oct 17Week 7@ SyracuseLiveLine−14.5Total56.5
8. Sat, Oct 31Week 9vs StanfordLine−22.5Total60.5
9. Sat, Nov 7Week 10@ Georgia TechLine−14.5Total61.5
10. Sat, Nov 14Week 11@ North CarolinaLine—Total—
11. Sat, Nov 21Week 12vs PittsburghLine—Total—
12. Sat, Nov 28Week 13@ KentuckyLine—Total—

Results are graded against the closing line, the last price posted before kickoff. Odds shown for reference only. If gambling stops being fun, call 1-800-GAMBLER.